Aug. 31, 2011
Adult stem cells are safe as well as feasible for treatment of stroke in patients, according to the published results of a ground-breaking Phase I trial from the University of Texas Health Science Center at Houston. Looking at ten patients in this first study, the researchers found no study-related severe adverse events, and while the study was not designed to determine effectiveness, the team found that most of the patients did better compared with matched untreated patients.
Dr. Sean Savitz, first author, said:
In order to bring stem cells forward as a potential new treatment for stroke patients, we have to establish safety first and this study provides the first evidence in addressing that goal. Now we are conducting two other stroke cell therapy studies examining safety and efficacy, one of which can be administered up to 19 days after someone has suffered a stroke.
Results of the study were published in the journal Annals of Neurology.