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Adult Stem Cells Help Patients With Spinal Cord Injury

by David Prentice
October 18, 2009

A new report by researchers in Portugal and at Wayne State University shows adult stem cells increased mobility and quality of life for spinal cord injury patients. Dr. Jean Peduzzi-Nelson collaborated with Dr. Carlos Lima and colleagues for the study, published in the journal Neurorehabilitation and Neural Repair.

The study follows 20 patients with severe chronic spinal cord injuries. All of the patients had total paralysis below the level of their spinal cord injury before the treatment, with treatment 18 months to 15 years after the injury. Patients received a combination of partial scar removal, transplantation of nasal tissue containing adult stem cells to the site of the spinal cord injury, and rehabilitation. All patients had no use of their legs before the treatment, while after treatment 13 patients improved in the standard measures used to assess functional independence and walking capabilities.

Dr. Peduzzi-Nelson noted:

“This may be the first clinical study of patients with severe, chronic spinal cord injury to report considerable functional improvement in some patients with a combination treatment. Normally, in people with spinal cord injuries that happened more than 18 months ago, there is little improvement.”

Lima and Peduzzi-Nelson had also published earlier results on 7 spinal cord injury patients; Lima also recently published a review on olfactory mucosa, the source of the cells for this treatment.

Dr. Peduzzi-Nelson and Dr. Jay Meythaler of Wayne State are seeking FDA approval to perform the procedure in the United States.


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Comments

By: ajf7688 Blog – FRC Blog » Adult Stem Cells Help Patients With Spinal Cord Injury | October 19, 2009 at 9:16 pm

[...] Read more: FRC Blog » Adult Stem Cells Help Patients With Spinal Cord Injury [...]

By: Dqrlene Price | October 19, 2009 at 11:23 pm

That is wonderful. How did the candidates get selected? Are they looking to take on any additional candidates and if so, how can you get on the list?

By: jamie peers | October 30, 2009 at 2:41 pm

I am very glad to see our universities partnering with overseas doctors/facilities to find procedures not presently going on in the US. I too am interested in finding out how I could get my son into such a program/procedure. He sounds like the perfect candidate and I would love to know more about this.

By: FRC Blog » “Next Year” for Embryonic Stem Cells? | October 31, 2009 at 8:24 am

[...] of adult stem cell success for spinal cord injury patients has already been published by groups in Portugal, in Australia, in Ecuador, and in [...]

By: sandycoley | November 5, 2009 at 3:48 pm

Wonderful! Would like to know if my son could be helped in this program. I would like to know more about this.

By: Reflections of a Paralytic » Event: Adult Stem Cells Saved My Life | November 9, 2009 at 11:43 am

[...] a quick browse through my Google Alerts of the past two weeks found these stories: Adult stem cells increased mobility for spinal cord injury patients Black Sabbath’s Tony Iommi ‘feeling great’ after stem-cell treatment on hand (I [...]

By: The Cloakroom » Geron Admits Politics in Timing of FDA Embryonic Stem Cell Approval | February 18, 2010 at 12:39 pm

[...] spinal cord patients recover movement and sensation. Laura Dominguez is one of those patients. The results have been published in peer-reviewed journals in 2005 and 2009. Tags: Geron, Stem [...]

By: FRC Blog » Adult Stem Cells Help Spinal Cord Get The Signal | February 26, 2010 at 3:01 pm

[...] can enhance remyelination and facilitate functional recovery after traumatic spinal cord injury. Patients have already been treated with similar nasal adult stem cells. The authors of this current study note that besides confirming [...]

By: FRC Blog » Adult Stem Cell Trial for Spinal Cord Injury in U.S. | August 4, 2010 at 2:55 pm

[...] stem cells from olfactory tissue have also been used to successfully treat spinal cord injury patients. window.fbAsyncInit = function() { FB.init({appId: "120153911335863", status: true, cookie: true, [...]

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